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Chronic kidney disease is a significant cause of illness and death in dogs and is often caused by glomerular diseases. A specific category of glomerular disease called immune complex-mediated glomerulonephritis (ICGN) accounts for approximately 50% of dogs that have a kidney biopsy due to suspicion of glomerular disease. The treatment for ICGN compared with other glomerular diseases differs in that immunosuppressive therapy is typically recommended. However, such therapy can be harmful in dogs without an immune-mediated component to their disease. Currently, ICGN can only be diagnosed with evaluation of a kidney biopsy, as there are no available biomarkers that can accurately identify this category of glomerular disease. Ongoing research is exploring potential biomarkers that could allow veterinarians to non-invasively diagnose ICGN. This would allow for more confidence in the appropriate treatment of dogs with this type of kidney disease, particularly in patients that are not good candidates for a kidney biopsy. This program has been RACE approved for 1 hour of continuing education credit in jurisdictions that recognize RACE approval